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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGEF2
All Species:
9.7
Human Site:
T152
Identified Species:
42.67
UniProt:
Q92974
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92974
NP_004714.2
986
111543
T152
S
L
A
K
S
V
S
T
T
N
I
A
G
H
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q60875
985
111926
T152
S
L
A
K
S
V
S
T
T
N
I
A
G
H
F
Rat
Rattus norvegicus
Q5FVC2
985
111891
T152
S
L
A
K
S
V
S
T
T
N
I
A
G
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413874
1407
158394
I511
A
L
S
K
S
V
S
I
Q
N
I
A
G
V
G
Frog
Xenopus laevis
NP_001129636
976
111755
T151
L
S
K
S
V
S
T
T
N
I
A
G
N
L
N
Zebra Danio
Brachydanio rerio
XP_689770
871
98879
R139
I
Y
P
S
E
T
L
R
Q
S
F
L
G
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
88.6
89.1
N.A.
N.A.
29.2
60.7
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
93.5
93.5
N.A.
N.A.
44.4
74.8
67
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
60
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
73.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
50
0
0
0
0
0
0
0
17
67
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
50
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
17
84
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% H
% Ile:
17
0
0
0
0
0
0
17
0
17
67
0
0
0
0
% I
% Lys:
0
0
17
67
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
17
67
0
0
0
0
17
0
0
0
0
17
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
17
67
0
0
17
0
17
% N
% Pro:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
17
% R
% Ser:
50
17
17
34
67
17
67
0
0
17
0
0
0
17
0
% S
% Thr:
0
0
0
0
0
17
17
67
50
0
0
0
0
0
0
% T
% Val:
0
0
0
0
17
67
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _